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Case of the Week 35 2015

*Newborn with respiratory distress. Failure to pass NG tube.

What is the most likely diagnosis?

Answer

Answer: Choanal atresia

Case Discussion:

CT images showed bilateral osseous choanal atresia (arrows) and retention of secretions.

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Choanal atresia is a narrowing or blockage of the nasal passage by abnormal bony or soft tissue. It is a congenital disorder and can be unilateral or bilateral.
• 90 % of cases are osseous (10 % membranous)
• 2/3 are unilateral (1/3 bilateral)

Diagnosis is confirmed by radiological imaging, usually CT scan.
• can demonstrate a uni or bilateral posterior nasal narrowing with an obstruction
• airway less than 3 mm at the level of the pterygoid plates in the axial plane
• Retention of secretions
• can demonstrate thickening of the vomer
• medial bowing of posterior maxillary sinus

References:
1. Hengerer AS, Brickman TM, Jeyakumar A. Choanal atresia: embryologic analysis and evolution of treatment, a 30-year experience. Laryngoscope. 2008;118 (5): 862-6.
2. Szeremeta W, Parikh TD, Widelitz JS. Congenital nasal malformations. Otolaryngol. Clin. North Am. 2007;40 (1): 97-112.
3. Tadmor R, Ravid M, Millet D et-al. Computed tomographic demonstration of choanal atresia. AJNR Am J Neuroradiol. 5 (6): 743-5.